Assembling genomes: Transforming Read-Pairs to Long Virtual Reads
Explore the process of genome assembly by transforming paired short DNA reads into longer virtual reads through paths in de Bruijn graphs. Understand how unique path identification enables constructing longer sequences computationally and the challenges posed by repetitive genomic regions during assembly.
We'll cover the following...
We'll cover the following...
Constructing de Bruijn graph from long reads
Let Reads be the collection of all k-mer reads taken from N read-pairs. Note that a read-pair formed by k-mer reads Read and Read ...