Epilogue: Complications in ori Predictions
Understand the challenges involved in predicting DNA replication origins in bacterial genomes, including variations in DnaA boxes, the shifted ter region, and complexities in skew diagrams. Explore how these factors affect computational identification and consider evolutionary hypotheses impacting ori predictions.
We'll cover the following...
We'll cover the following...
In this lesson, we’ve considered three genomes and found three different hypothesized 9-mers encoding DnaA boxes: ATGATCAAG in Vibrio cholerae, CCTACCACC in Thermotoga petrophila, and TTATCCACA in E. coli. We must warn you that finding ori is ...