Open Problem: Finding Replication Origins in Archaea
Explore the complexities of finding replication origins in archaea, organisms distinct from bacteria and eukaryotes. Learn about the unique genomic features of archaea, analyze skew diagrams, and understand why computational tools to accurately identify multiple replication origins are still needed.
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Archaea are unicellular organisms so distinct from other life forms that biologists have placed them into their own domain of life separate from bacteria and eukaryotes. Although archaea are visually similar to bacteria, they have some genomic features that are more closely related to eukaryotes. In particular, the replication machinery of archaea is more similar to eukaryotes than bacteria. Yet archaea use a much greater variety of energy sources ...