Deamination
Explore the process of deamination and its role in DNA replication, focusing on how single-stranded DNA regions experience higher mutation rates. Understand the nucleotide imbalances caused by deamination and how this affects genome integrity during replication.
We'll cover the following...
We'll cover the following...
In the last section, we saw that as the replication fork expands, DNA polymerase synthesizes DNA quickly on the reverse half-strand but suffers delays on the forward half-strand. Notice that since the replication of a reverse half-strand proceeds quickly, it ...