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DnaA Boxes

Explore the role of DnaA boxes in marking the initiation site of bacterial DNA replication. Understand how specific nucleotide sequences guide replication start points and develop computational approaches to detect these signals within bacterial genomes.

We'll cover the following...

Initiation of replication

In the rest of this section, we’ll focus on the relatively easy case of finding ori in bacterial genomes, most of which consist of a single circular chromosome. Research has shown that the region of the bacterial genome encoding ori is typically a few ...