How Do Bacteria Make Antibiotics?

Explore the process by which bacteria produce antibiotics, focusing on the central dogma of molecular biology. Understand how DNA transcription creates RNA, which is then translated into amino acid sequences forming antibiotics. This lesson helps you grasp the computational translation of RNA codons into proteins.

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How peptides are encoded by the genome

How peptides are encoded by the genome

Let’s begin by considering Tyrocidine B1, one of many antibiotics produced by Bacillus brevis. Tyrocidine B1 is defined by the 10 amino acid-long sequence shown below (using both the one-letter and three-letter notations for amino acids). Our goal in this lesson is to figure out how Bacillus brevis could have made this antibiotic.

Val $\space$ - $\space$ Lys $\space$ - $\space$ Leu $\space$ - $\space$ Phe $\space$ - $\space$ Pro $\space$ - $\space$ Trp $\space$ - $\space$ Phe $\space$ - ...

1.Before Getting Started

2.Where in the Genome Does DNA Replication Begin?

3.DNA Replication: Open Problems, Charging Stations, and Detours

4.How Do We Assemble Genomes?

5.Assemble Genomes: Charging Stations, and Detours

6.How Do We Compare Biological Sequences?

7.Biological Sequences: Detours

8.Conclusion

How Do Bacteria Make Antibiotics?

How peptides are encoded by the genome